EPHB4 (Human) Recombinant Protein
产品名称： EPHB4 (Human) Recombinant Protein
英文名称： EPHB4 (Human) Recombinant Protein
产品编号： P5709
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
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- Specification
- Product Description:
- Human EPHB4 (NP_004435.3, 577 a.a. - 987 a.a.) partial recombinant protein with GST tag expressed in Baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 73
- Form:
- Liquid
- Preparation Method:
- Baculovirus infected insect cell (Sf29) expression system
- Purification:
- Glutathione sepharose chromatography and anion exchange chromatography
- Purity:
- 82 % by SDS-PAGE/CBB staining.
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg (or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip™3000.
Substrate : Blk/Lyntide. ATP: 100 µM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.1% CHAPS, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 2050
- Protein Accession#:
- NP_004435.3
- Gene Name:
- EPHB4
- Gene Alias:
- HTK,MYK1,TYRO11
- Gene Description:
- EPH receptor B4
- Omim ID:
- 600011
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq
- Other Designations:
- ephrin receptor EphB4,hepatoma transmembrane kinase,soluble EPHB4 variant 1,soluble EPHB4 variant 2,soluble EPHB4 variant 3
- Gene Pathway
- Related Disease